BACTERICIDAL ACTIVITY OF SPARFLOXACIN AND CIPROFLOXACIN UNDER ANAEROBIC CONDITIONS

被引：19

作者：

COOPER, MA

ANDREWS, JM

WISE, R

机构：

[1] Department of Medical Microbiology, Birmingham, Dudley Road Hospital

来源：

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY | 1991年 / 28卷 / 03期

关键词：

D O I：

10.1093/jac/28.3.399

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

The kill kinetics of sparfloxacin and ciprofloxacin have been investigated under anaerobic conditions against Bacteroides fragilis and Escherichia coli. The results for E. coli were compared with those obtained under aerobic conditions. It was found that the quinolones were bactericidal under anaerobic conditions. This bactericidal activity is inhibited by the presence of chloramphenicol, a known protein synthesis inhibitor. Filamentation was seen with B. fragilis after 2 h exposure to either agent. © 1991, by The British Society for Antimicrobial Chemotherapy.

引用

页码：399 / 405

页数：7

共 15 条

[1]

BRYAN L E, 1979, Antimicrobial Agents and Chemotherapy, V15, P7

[2] RELATIONSHIP BETWEEN METRONIDAZOLE METABOLISM AND BACTERICIDAL ACTIVITY [J].