CYTOSTATIN, A NOVEL INHIBITOR OF CELL-ADHESION TO COMPONENTS OF EXTRACELLULAR-MATRIX PRODUCED BY STREPTOMYCES SP MJ654-NF4 .2. PHYSICOCHEMICAL PROPERTIES AND STRUCTURE DETERMINATION

被引：36

作者：

AMEMIYA, M

SOMENO, T

SAWA, R

NAGANAWA, H

ISHIZUKA, M

TAKEUCHI, T

机构：

[1] MCRF,INST CHEMOTHERAPY,NUMAZU,SHIZUOKA 41003,JAPAN

[2] MCRF,INST MICROBIAL CHEM,SHINAGAWA KU,TOKYO 141,JAPAN

来源：

JOURNAL OF ANTIBIOTICS | 1994年 / 47卷 / 05期

关键词：

D O I：

10.7164/antibiotics.47.541

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The structure of cytostatin was determined to be 5,6-dihydro-5-methyl-6-(6-hydroxy-1,5-dimethyl-4-phosphonooxy-7,9,11-tridecatrienyl)-2H-pyran-2-one sodium salt on the basis of physico-chemical properties and NMR studies.

引用

页码：541 / 544

页数：4

共 8 条

[1] CYTOSTATIN, A NOVEL INHIBITOR OF CELL-ADHESION TO COMPONENTS OF EXTRACELLULAR-MATRIX PRODUCED BY STREPTOMYCES SP MJ654-NF4 .1. TAXONOMY, FERMENTATION, ISOLATION AND BIOLOGICAL-ACTIVITIES [J].

AMEMIYA, M ;

UENO, M ;

OSONO, M ;

MASUDA, T ;

KINOSHITA, N ;

NISHIDA, C ;

HAMADA, M ;

ISHIZUKA, M ;

TAKEUCHI, T .

JOURNAL OF ANTIBIOTICS, 1994, 47 (05) :536-540

[2] H-1 AND C-13 ASSIGNMENTS FROM SENSITIVITY-ENHANCED DETECTION OF HETERONUCLEAR MULTIPLE-BOND CONNECTIVITY BY 2D MULTIPLE QUANTUM NMR [J].

BAX, A ;

SUMMERS, MF .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1986, 108 (08) :2093-2094

[3] NATURAL ABUNDANCE N-15 NMR BY ENHANCED HETERONUCLEAR SPECTROSCOPY [J].

BODENHAUSEN, G ;

RUBEN, DJ .

CHEMICAL PHYSICS LETTERS, 1980, 69 (01) :185-189

[4] ASSIGNMENT OF COMPLEX H-1-NMR SPECTRA VIA TWO-DIMENSIONAL HOMONUCLEAR HARTMANN-HAHN SPECTROSCOPY [J].

DAVIS, DG ;

BAX, A .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1985, 107 (09) :2820-2821

[5] NOVEL ANTITUMOR AGENTS CI-920, PD 113270, AND PD 113271 .3. STRUCTURE DETERMINATION [J].

HOKANSON, GC ;

FRENCH, JC .

JOURNAL OF ORGANIC CHEMISTRY, 1985, 50 (04) :462-466

[6] SULTRIECIN, A NEW ANTIFUNGAL AND ANTITUMOR ANTIBIOTIC FROM STREPTOMYCES-ROSEISCLEROTICUS - PRODUCTION, ISOLATION, STRUCTURE AND BIOLOGICAL-ACTIVITY [J].

OHKUMA, H ;

NARUSE, N ;

NISHIYAMA, Y ;

TSUNO, T ;

HOSHINO, Y ;

SAWADA, Y ;

KONISHI, M ;

OKI, T .

JOURNAL OF ANTIBIOTICS, 1992, 45 (08) :1239-1249

[7]

SCOTT AI, 1964, INTERPRETATION ULTRA, P53

[8] NOVEL ANTI-TUMOR AGENTS CI-920, PD 113,270 AND PD 113,271 .2. ISOLATION AND CHARACTERIZATION [J].

STAMPWALA, SS ;

BUNGE, RH ;

HURLEY, TR ;

WILLMER, NE ;

BRANKIEWICZ, AJ ;

STEINMAN, CE ;

SMITKA, TA ;

FRENCH, JC .

JOURNAL OF ANTIBIOTICS, 1983, 36 (12) :1601-1605

← 1 →