LIGHT-MICROSCOPIC AND IMMUNOHISTOCHEMICAL FEATURES IN SERIAL BIOPSIES OF EPIDERMAL VERSUS DERMAL ALLOGRAFTS

被引:5
作者
HOFFMAN, DK
SIBLEY, RK
KORMAN, JM
PRESS, BHJ
机构
[1] STANFORD UNIV,MED CTR,SCH MED,DIV PLAST & RECONSTRUCT SURG,NC-104,STANFORD,CA 94305
[2] STANFORD UNIV,MED CTR,SCH MED,DEPT PATHOL,STANFORD,CA 94305
关键词
D O I
10.1097/00000637-199409000-00010
中图分类号
R61 [外科手术学];
学科分类号
摘要
The local immune response to allograft dermis and epidermis was studied in a rat skin-graft model. Biopsies taken at varying times after transplantation were analyzed using routine light microscopy and a panel of monoclonal antibodies. The dermis appeared to be spared by the rejection process, whereas the epithelium and adnexal elements of the dermis were destroyed. The persistence of dermis transplanted across major histoincompatibilities may allow it to be useful in reconstructing large skin losses.
引用
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页码:295 / 299
页数:5
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