TRANSLATION OF THE OPEN READING FRAME ENCODED BY COMS, A GENE OF THE SRF OPERON, IS NECESSARY FOR THE DEVELOPMENT OF GENETIC COMPETENCE, BUT NOT SURFACTIN BIOSYNTHESIS, IN BACILLUS-SUBTILIS

被引：14

作者：

DSOUZA, C ^{[1
]}

NAKANO, MM ^{[1
]}

FRISBY, DL ^{[1
]}

ZUBER, P ^{[1
]}

机构：

[1] LOUISIANA STATE UNIV,MED CTR,DEPT BIOCHEM & MOLEC BIOL,SHREVEPORT,LA 71130

来源：

JOURNAL OF BACTERIOLOGY | 1995年 / 177卷 / 14期

关键词：

D O I：

10.1128/jb.177.14.4144-4148.1995

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

A small open reading frame, comS of the srf operon, is the site of mutations that impair competence development in Bacillus subtilis. comS open reading frame translation was required for competence, as was confirmed by the suppression of a comS amber mutation [comS(Am)] by the nonsense suppressor sup-3. comS(Am), when introduced into the srf operon, eliminated late competence gene expression but had no significant effect on surfactin production.

引用

页码：4144 / 4148

页数：5

共 43 条

[1] NUCLEOTIDE-SEQUENCE AND GENETIC ORGANIZATION OF THE BACILLUS-SUBTILIS COMG OPERON
ALBANO, M
BREITLING, R
DUBNAU, DA
[J]. JOURNAL OF BACTERIOLOGY, 1989, 171 (10) : 5386 - 5404
[2] HIGH-EFFICIENCY GENE INACTIVATION AND REPLACEMENT SYSTEM FOR GRAM-POSITIVE BACTERIA
BISWAS, I
GRUSS, A
EHRLICH, SD
MAGUIN, E
[J]. JOURNAL OF BACTERIOLOGY, 1993, 175 (11) : 3628 - 3635
[3] SEQUENCE AND ANALYSIS OF THE GENETIC-LOCUS RESPONSIBLE FOR SURFACTIN SYNTHESIS IN BACILLUS-SUBTILIS
COSMINA, P
RODRIGUEZ, F
DEFERRA, F
GRANDI, G
PEREGO, M
VENEMA, G
VANSINDEREN, D
[J]. MOLECULAR MICROBIOLOGY, 1993, 8 (05) : 821 - 831
[4] IDENTIFICATION OF COMS, A GENE OF THE SRFA OPERON THAT REGULATES THE ESTABLISHMENT OF GENETIC COMPETENCE IN BACILLUS-SUBTILIS
DSOUZA, C
NAKANO, MM
ZUBER, P
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1994, 91 (20) : 9397 - 9401
[5] AMINO-ACYLATION SITE MUTATIONS IN AMINO ACID-ACTIVATING DOMAINS OF SURFACTIN SYNTHETASE - EFFECTS ON SURFACTIN PRODUCTION AND COMPETENCE DEVELOPMENT IN BACILLUS-SUBTILIS
DSOUZA, C
NAKANO, MM
CORBELL, N
ZUBER, P
[J]. JOURNAL OF BACTERIOLOGY, 1993, 175 (11) : 3502 - 3510
[6] FATE OF TRANSFORMING DNA FOLLOWING UPTAKE BY COMPETENT BACILLUS-SUBTILIS
DUBNAU, D
DAVIDOFF.R
[J]. JOURNAL OF MOLECULAR BIOLOGY, 1971, 56 (02) : 209 - &
[7] 2-COMPONENT REGULATORS AND GENETIC COMPETENCE IN BACILLUS-SUBTILIS
DUBNAU, D
HAHN, J
ROGGIANI, M
PIAZZA, F
WEINRAUCH, Y
[J]. RESEARCH IN MICROBIOLOGY, 1994, 145 (5-6) : 403 - 411
[8] Dubnau David, 1993, P555
[9] NUCLEOTIDE-SEQUENCE OF 5' PORTION OF SRFA THAT CONTAINS THE REGION REQUIRED FOR COMPETENCE ESTABLISHMENT IN BACILLUS-SUBTILIS
FUMA, S
FUJISHIMA, Y
CORBELL, N
DSOUZA, C
NAKANO, MM
ZUBER, P
YAMANE, K
[J]. NUCLEIC ACIDS RESEARCH, 1993, 21 (01) : 93 - 97
[10] CHARACTERIZATION OF THE SURFACTIN SYNTHETASE MULTIENZYME COMPLEX
GALLI, G
RODRIGUEZ, F
COSMINA, P
PRATESI, C
NOGAROTTO, R
DEFERRA, F
GRANDI, G
[J]. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY, 1994, 1205 (01): : 19 - 28

← 1 2 3 4 5 →