DISCODERMINS-F-H, CYTOTOXIC AND ANTIMICROBIAL TETRADECAPEPTIDES FROM THE MARINE SPONGE DISCODERMIA-KIIENSIS - STRUCTURE REVISION OF DISCODERMINS-A-D

被引：37

作者：

RYU, G

MATSUNAGA, S

FUSETANI, N

机构：

[1] Laboratory of Marine Biochemistry, Faculty of Agriculture, University of Tokyo, Bunkyo-ku, Tokyo

来源：

TETRAHEDRON | 1994年 / 50卷 / 47期

关键词：

D O I：

10.1016/S0040-4020(01)89347-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Three new cytotoxic and antimicrobial peptides, discodermins F (6), G (7), and H (8), have been isolated from the marine sponge Discodermia kiiensis. The structures of 6-8 were determined by interpretation of spectral data and chemical degradation. Structures of discodermins A-D were revised on the basis of NMR data and protein sequence analysis.

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页码：13409 / 13416

页数：8

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