EFFECT OF ABO BLOOD-GROUP AND SECRETOR STATUS ON THE FREQUENCY OF HELICOBACTER-PYLORI ANTIBODIES

被引:40
作者
HOOKNIKANNE, J [1 ]
SISTONEN, P [1 ]
KOSUNEN, TU [1 ]
机构
[1] FINNISH RED CROSS & BLOOD TRANSFUS SERV,HELSINKI,FINLAND
关键词
ABO blood groups; Blood donors; Duodenal ulcer; Helicobacter pylori; Helicobacter pylori antibodies; Secretor status;
D O I
10.3109/00365529008999220
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Duodenal ulcer is associated with such genetic characteristics as blood group O and secretor status. Since Helicobacter pylori has been proved to be an important factor in the pathogenesis of duodenal ulcer, we wanted to study whether the frequency of H. pylori antibodies would vary in individuals with different blood group antigens. Antibodies against H. pylori were determined in 271 blood donors. Acid glycine extract from an H. pylori strain was used as antigen in enzyme immunoassay. Our results suggested no significant association of increased levels of H. pylori antibodies with ABO blood group and secretor status, which implies that H. pylori infection is not associated with the ABO group and secretor status. Thus H. pylori and blood group antigens seem to be independently linked to duodenal ulcer. © 1990 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.
引用
收藏
页码:815 / 818
页数:4
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