GAS-CHROMATOGRAPHIC SCREENING-PROCEDURE FOR ACID AND NEUTRAL-DRUGS IN BLOOD

被引：27

作者：

FOERSTER, EH ^{[1
]}

DEMPSEY, J ^{[1
]}

GARRIOTT, JC ^{[1
]}

机构：

[1] SW INST FORENS SCI,TOXICOL LAB,POB 35728,DALLAS,TX 75235

来源：

JOURNAL OF ANALYTICAL TOXICOLOGY | 1979年 / 3卷 / 03期

关键词：

D O I：

10.1093/jat/3.3.87

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A relatively simple extraction procedure for the comprehensive screening of acid, neutral, and many basic drugs is described. The procedure Involves a single extraction into toluene-ether, evaporation, and combined dissolution and clean-up of the residue using ethanol and hexane. The ethanol phase Is used for analysis by gas chromatography using a flame-Ionization detector. More than 80 components have been detected and identified In blood by the procedure. The procedure can be used as a routine screen In clinical toxicology cases with results available within two hours. © 1979 Oxford University Press.

引用

页码：87 / 91

页数：5