ELECTROPHORETICALLY-MEDIATED MICROANALYSIS (EMMA)

被引:52
作者
REGNIER, FE
PATTERSON, DH
HARMON, BJ
机构
[1] PERSEPT BIOSYST INC,CAMBRIDGE,MA 02139
[2] MIT,CTR BIOTECHNOL PROC ENGN,CAMBRIDGE,MA 02139
关键词
D O I
10.1016/0165-9936(95)98316-Z
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
This article describes a microanalytical technique for carrying out separations and chemical assays on biological samples at the zeptomole level using capillary electrophoretic systems. It is shown that through the use of high sensitivity detection systems, such as laser induced fluorescence, it is possible to detect components in single cells and even to detect single molecules of enzymes.
引用
收藏
页码:177 / 181
页数:5
相关论文
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