22-TRANS-CHOLESTA-5,22,24-TRIEN-3BETA-OL - AN INTERMEDIATE IN CONVERSION OF STIGMASTEROL TO CHOLESTEROL IN TOBACCO HORNWORM, MANDUCA SEXTA (JOHANNSON)

被引：34

作者：

SVOBODA, JA

HUTCHINS, RF

THOMPSON, MJ

ROBBINS, WE

机构：

[1] Insect Physiology Laboratory, Agricultural Research Service, U. S. Department of Agriculture Beltsville

来源：

STEROIDS | 1969年 / 14卷 / 05期

关键词：

D O I：

10.1016/S0039-128X(69)80041-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A new sterol, 22-trans-cholesta-5,22,24-trien-3β-ol, was isolated and identified as an intermediate in the conversion of stigmasterol to cholesterol in the tobacco hornworm. This intermediate, which is normally present in stigmasterol-fed insects, accumulates when the conversion of stigmasterol to cholesterol is inhibited by 20,25-diazacholesterol. Synthetic 22-trans-cholesta-5,22,24-trien-3β-ol supported normal growth and development and was converted to cholesterol by the tobacco hornworm. © 1968 Holden-Day, Inc.

引用

页码：469 / &

共 12 条

[1] THE CONVERSION OF DELTA4-CHOLESTENE-3-ONE TO CHOLESTEROL [J].