This progress report demonstrates a pseudomonas vaccine and hyperimmune plasma used in treating 61 patients with burns involving a minimum of 20 percent of the body with full‐thickness (third degree) loss of 40 percent total injury (partial thickness and full‐thickness). The incidence of septicemia had decreased and mortality due to pseudomonas septicemia, when it does occur, has been greatly reduced. Copyright © 1968, Wiley Blackwell. All rights reserved