RAT PINEAL GS-ALPHA, GI-ALPHA AND GO-ALPHA - RELATIVE ABUNDANCE AND DEVELOPMENT

被引：13

作者：

BABILA, T ^{[1
]}

SCHAAD, NC ^{[1
]}

KLEIN, DC ^{[1
]}

机构：

[1] NICHHD,DEV NEUROBIOL LAB,NEUROENDOCRINOL SECT,BETHESDA,MD 20892

来源：

BRAIN RESEARCH | 1992年 / 572卷 / 1-2期

关键词：

GS; GI; GO; GTP-BINDING PROTEIN; PINEAL; DEVELOPMENT;

D O I：

10.1016/0006-8993(92)90474-N

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The adult rat pineal gland contains relatively high concentrations of Gs-alpha, low amounts of both Gi-alpha and Go-alpha, and undetectable levels of GT-alpha. During development the amounts of 45 kDa Gs-alpha and of Gi-alpha remain constant. In contrast, 42 kDa Gs-alpha and Go-alpha are nearly absent at birth and increase in abundance markedly thereafter. GT-alpha is undetectable at any age. It would appear that multiple mechanisms regulate the expression of G-proteins in the pineal gland.

引用

页码：232 / 235

页数：4

共 24 条

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