CATALYSED HYDROLYSIS OF AN ACYL-ACTIVATED ANILIDE IN BUFFERED SOLUTIONS

被引：14

作者：

PRATT, RF

LAWLOR, JM

机构：

[1] Department of Chemistry, University of Melbourne

来源：

JOURNAL OF THE CHEMICAL SOCIETY B-PHYSICAL ORGANIC | 1969年 / 03期

关键词：

D O I：

10.1039/j29690000230

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The hydrolysis of N-(4-nitrophenyl)dichloroacetamide is catalysed by buffer reagents acting as general acids and bases. The dihydrogen phosphate, dihydrogen arsenate, and hydrogen carbonate ions are abnormally effective as general-acid catalysts, and the carbonate ion is probably abnormally effective as a general base. The results of this study do not lend support to the concept of bifunctional catalysis, and are discussed in terms of hypothetical energy-reaction-co-ordinate profiles for proton transfer.

引用

页码：230 / &

共 23 条

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