CATALYSED HYDROLYSIS OF AN ACYL-ACTIVATED ANILIDE IN BUFFERED SOLUTIONS

被引:14
作者
PRATT, RF
LAWLOR, JM
机构
[1] Department of Chemistry, University of Melbourne
来源
JOURNAL OF THE CHEMICAL SOCIETY B-PHYSICAL ORGANIC | 1969年 / 03期
关键词
D O I
10.1039/j29690000230
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The hydrolysis of N-(4-nitrophenyl)dichloroacetamide is catalysed by buffer reagents acting as general acids and bases. The dihydrogen phosphate, dihydrogen arsenate, and hydrogen carbonate ions are abnormally effective as general-acid catalysts, and the carbonate ion is probably abnormally effective as a general base. The results of this study do not lend support to the concept of bifunctional catalysis, and are discussed in terms of hypothetical energy-reaction-co-ordinate profiles for proton transfer.
引用
收藏
页码:230 / &
相关论文
共 23 条