T-LYMPHOCYTES INHIBITING FACTORS IN RENAL CANCER - EVALUATION OF DIFFERENCES BETWEEN ARTERIAL AND RENAL VENOUS-BLOOD LEVELS OF E-ROSETTE FORMING CELLS

被引:7
作者
CARMIGNANI, G [1 ]
BELGRANO, E [1 ]
PUPPO, P [1 ]
CORNAGLIA, P [1 ]
机构
[1] UNIV GENOA,DEPT MED,I-16132 GENOA,ITALY
关键词
D O I
10.1016/S0022-5347(17)57323-1
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
The cellular immune response has been reported to be impaired in patients with renal cancer and to be increased by removal of the tumor bulk. T lymphocyte levels in the vein of the neoplastic kidney were investigated in 4 patients to assess the presence of a T lymphocyte inhibiting factor produced by the tumor. T lymphocyte levels resulted in significantly decreased tumorous venous blood, whether compared to arterial, contralateral or peripheral blood. A similar result was not found in 10 control patients. Some hypotheses on the nature of this T lymphocyte inhibition are discussed.
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页码:673 / 675
页数:3
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