INHIBITION OF BOVINE PAPILLOMAVIRUS PLASMID DNA-REPLICATION BY ADENOASSOCIATED VIRUS

被引：60

作者：

HERMONAT, PL ^{[1
]}

机构：

[1] UNIV ARKANSAS MED SCI HOSP,DEPT MICROBIOL & IMMUNOL,LITTLE ROCK,AR 72205

来源：

VIROLOGY | 1992年 / 189卷 / 01期

关键词：

D O I：

10.1016/0042-6822(92)90710-7

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The helper-dependent human parvovirus adeno-associated virus type 2 (AAV) inhibits both the oncogenic transforming abilities and the DNA replication of its helper viruses, adenovirus (Ad), and herpes simplex virus (HSV). As AAV-2 also inhibits the transforming ability of bovine papillomavirus type 1 (BPV), AAV-2 was assayed for its ability to inhibit BPV plasmid DNA replication. Here we find that the AAV-2 Rep78 gene is able to trans-inhibit BPV plasmid DNA replication and that the AAV-2 terminal repeats (TR) are also cis-required for the full inhibitory effect of AAV-2. When both the AAV-2 Rep78 open reading frame and TRs are present the inhibition of BPV plasmid DNA replication is very strong. © 1992.

引用

页码：329 / 333

页数：5

共 55 条

[31] MOUSE CELLS TRANSFORMED BY BOVINE PAPILLOMAVIRUS CONTAIN ONLY EXTRACHROMOSOMAL VIRAL-DNA SEQUENCES [J].

LAW, MF ;

LOWY, DR ;

DVORETZKY, I ;

HOWLEY, PM .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1981, 78 (05) :2727-2731

[32] INVITRO TUMORIGENIC TRANSFORMATION BY A DEFINED SUB-GENOMIC FRAGMENT OF BOVINE PAPILLOMA-VIRUS DNA [J].

LOWY, DR ;

DVORETZKY, I ;

SHOBER, R ;

LAW, MF ;

ENGEL, L ;

HOWLEY, PM .

NATURE, 1980, 287 (5777) :72-74

[33] CHARACTERIZATION OF THE BOVINE PAPILLOMA-VIRUS PLASMID MAINTENANCE SEQUENCES [J].

LUSKY, M ;

BOTCHAN, MR .

CELL, 1984, 36 (02) :391-401

[34] INFLUENCE OF ADENO-ASSOCIATED SATELLITE VIRUS ON ADENOVIRUS-INDUCED TUMORS IN HAMSTERS [J].

MAYOR, HD ;

HOULDITC.GS ;

MUMFORD, DM .

NATURE-NEW BIOLOGY, 1973, 241 (106) :44-46

[35] ANTIBODIES TO ADENO-ASSOCIATED SATELLITE VIRUS AND HERPES-SIMPLEX IN SERA FROM CANCER-PATIENTS AND NORMAL ADULTS [J].

MAYOR, HD ;

DRAKE, S ;

STAHMANN, J ;

MUMFORD, DM .

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 1976, 126 (01) :100-104

[36] SEQUENCES REQUIRED FOR COORDINATE INDUCTION OF ADENOASSOCIATED VIRUS-P19 AND VIRUS-P40 PROMOTERS BY REP PROTEIN [J].

MCCARTY, DM ;

CHRISTENSEN, M ;

MUZYCZKA, N .

JOURNAL OF VIROLOGY, 1991, 65 (06) :2936-2945

[37] IDENTIFICATION OF THE TRANS-ACTING REP PROTEINS OF ADENOASSOCIATED VIRUS BY ANTIBODIES TO A SYNTHETIC OLIGOPEPTIDE [J].

MENDELSON, E ;

TREMPE, JP ;

CARTER, BJ .

JOURNAL OF VIROLOGY, 1986, 60 (03) :823-832

[38] TARGETING THE E1 REPLICATION PROTEIN TO THE PAPILLOMAVIRUS ORIGIN OF REPLICATION BY COMPLEX-FORMATION WITH THE E2 TRANSACTIVATOR [J].

MOHR, IJ ;

CLARK, R ;

SUN, S ;

ANDROPHY, EJ ;

MACPHERSON, P ;

BOTCHAN, MR .

SCIENCE, 1990, 250 (4988) :1694-1699

[39] EXPRESSION OF THE RAS ONCOGENE IN GYNECOLOGIC TUMORS [J].

OBRIEN, TJ ;

BANNON, GA ;

BARD, DS ;

HARDIN, JW ;

QUIRK, JG .

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 1989, 160 (02) :344-352

[40] INHIBITION OF ADENOVIRUS-TRANSFORMED CELL ONCOGENICITY BY ADENO-ASSOCIATED VIRUS [J].

OSTROVE, JM ;

DUCKWORTH, DH ;

BERNS, KI .

VIROLOGY, 1981, 113 (02) :521-533

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