6-NITROBENZOTRIAZOL-1-YLOXYTRIS(DIMETHYLAMINO)PHOSPHONIUM HEXAFLUOROPHOSPHATE(NBOP) - A NEW COUPLING REAGENT IN OLIGONUCLEOTIDE SYNTHESIS

被引：6

作者：

HASHMI, SAN ^{[1
]}

ADIRAJ, M ^{[1
]}

KUMAR, A ^{[1
]}

KATTI, SB ^{[1
]}

机构：

[1] CENT DRUG RES INST, DIV BIOPOLYMERS, LUCKNOW 226001, UTTAR PRADESH, INDIA

来源：

NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS | 1994年 / 13卷 / 05期

关键词：

D O I：

10.1080/15257779408011879

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

6-Nitrobenzotriazol-1-yloxytris(dimethylamino) phosphonium hexafluorophosphate (NBOP, 2) has been demonstrated as an efficient coupling reagent in oligonucleotide synthesis. The reagent is stable and gives high coupling yields without any side products.

引用

页码：1059 / 1067

页数：9