A DIRECT METHOD FOR THE SYNTHESIS OF POLYFUNCTIONALIZED UNSATURATED CARBONYL DERIVATIVES BY MICHAEL ADDITION OF NITROALKANES TO ENEDIONES WITH THE HELP OF DBU

被引：62

作者：

BALLINI, R

BOSICA, G

机构：

[1] Dipartimento di Scienze Chimiche dell'Università, I-62032 Camerino

来源：

TETRAHEDRON | 1995年 / 51卷 / 14期

关键词：

D O I：

10.1016/0040-4020(95)00136-V

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The Michael addition of several nitroalkanes to dimethyl maleate, (Z)-3-hexene-2,5-dione, N-ethyl maleimide, and N-phenyl maleimide, in MeCN or THF, proceeds very efficiently on DBU as base, and furnishes good to high yields of polyfunctionalized or saturated carbonyl derivatives.

引用

页码：4213 / 4222

页数：10

共 18 条

[1] APSIMON J, 1988, TOTAL SYNTHESIS NATU
[2] MICHAEL ADDITION OF NITROALKANES TO DIMETHYL MALEATE WITH DBU - A NEW DIRECT METHOD FOR THE SYNTHESIS OF POLYFUNCTIONALIZED ALPHA,BETA-UNSATURATED ESTERS
BALLINI, R
RINALDI, A
[J]. TETRAHEDRON LETTERS, 1994, 35 (49) : 9247 - 9250
[3] BALLINI R, 1987, SYNTHESIS-STUTTGART, P71
[4] BERGMAN ED, 1959, ORG REACTIONS, V10, P779
[5] CLOUGH JM, 1991, COMPREHENSIVE ORGANI, V3, P861
[6] Corey E J, 1989, LOGIC CHEM SYNTHESIS
[7] Demuth M., 1991, COMPREHENSIVE ORGANI, V5, P215, DOI DOI 10.1016/B978-0-08-052349-1.00125-6
[8] STEREOSELECTIVE SYNTHESIS OF SUBSTITUTED OXETANES
GALATSIS, P
PARKS, DJ
[J]. TETRAHEDRON LETTERS, 1994, 35 (36) : 6611 - 6614
[9] HWU JR, 1992, TETRAHEDRON LETT, V33, P6469
[10] Lee V. J., 1991, COMPREHENSIVE ORGANI, V4, P69

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