BIOACTIVE GLASS VERSUS HYDROXYLAPATITE IN RECONSTRUCTION OF OSTEOCHONDRAL DEFECTS IN THE RABBIT

被引：36

作者：

HEIKKILA, JT

AHO, AJ

YLIURPO, A

ANDERSSON, OH

AHO, HJ

HAPPONEN, RP

机构：

[1] TURKU UNIV, CENT HOSP, DEPT PATHOL, TURKU, FINLAND

[2] TURKU UNIV, DEPT PROSTCHODONT, TURKU, FINLAND

[3] TURKU UNIV, INST DENT, DEPT ORAL & MAXILLOFACIAL SURG, TURKU, FINLAND

[4] ABO AKAD UNIV, DEPT CHEM ENGN, TURKU, FINLAND

来源：

ACTA ORTHOPAEDICA SCANDINAVICA | 1993年 / 64卷 / 06期

关键词：

D O I：

10.3109/17453679308994597

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

摘要：

We studied osseointegration of a bioactive glass (BG) and hydroxylapatite (HA) in rabbit femur epiphyseal and metaphyseal regions. 17 BG and 24 HA cones implanted in defects through arthrotomy were analyzed. The holes for implants were drilled through distal femur joint surfaces. The cartilage wound repaired generally by fibrous tissue. Histomorphometry showed that 61, 78, and 79 percent of BG surface was covered by bone at 3, 6, and 12 weeks, respectively. The corresponding figures for HA were 47, 67, and 78 percent. Chemical bonding between bone and implants of both types was confirmed by scanning electron microscopy (SEM) and energy-dispersive x-ray analysis (EDXA). Formation of a calcium phosphaterich layer on the surface BG implant was demonstrated by EDXA. Our results indicate that the osseointegration rate of bioactive glass does not differ from that of hydroxylapatite.

引用

页码：678 / 682

页数：5