TRIFLUOROMETHYLATION OF AROMATIC-COMPOUNDS WITH SODIUM TRIFLUOROMETHANESULFINATE UNDER OXIDATIVE CONDITIONS

被引：381

作者：

LANGLOIS, BR

LAURENT, E

ROIDOT, N

机构：

[1] Lab. de Chimie Organique 3, associé au C.N.R.S., Université Claude Bernard, F 69622 Villeurbanne, 43 Bd du

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 51期

关键词：

TRIFLUOROMETHYLATION; AROMATIC COMPOUNDS; SODIUM TRIFLUOROMETHANESULFINATE; TERT-BUTYL HYDROPEROXIDE; COPPER(II) CATALYST;

D O I：

10.1016/0040-4039(91)80524-A

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Electron-rich aromatic compounds are trifluoromethylated with sodium trifluoromethanesulfinate and t-butyl hydroperoxide. Monotrifluoromethylation predominates in the presence of catalytic amounts of Cu(II) triflate whereas mono- and bis-trifluoromethylated aromatics are obtained in almost equal quantities in the absence of Cu(II).

引用

页码：7525 / 7528

页数：4