DELAYED-HYPERSENSITIVITY, IMMUNE DEVIATION, ANTIGEN-PROCESSING AND T-CELL SUBSET-SELECTION IN SYPHILIS PATHOGENESIS AND VACCINE DESIGN

被引：28

作者：

SELL, S ^{[1
]}

HSU, PL ^{[1
]}

机构：

[1] UNIV ARKANSAS, DEPT PATHOL, LITTLE ROCK, AR 72205 USA

来源：

IMMUNOLOGY TODAY | 1993年 / 14卷 / 12期

关键词：

D O I：

10.1016/0167-5699(93)90196-R

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

T-cell mediated delayed-type hypersensitivity (DTH) is the predominant immune mechanism for clearing tissues of infecting organisms in the primary lesion of syphilis. Here, Stewart Sell and Pei-Ling Hsu propose a strategy for vaccination against syphilis in which selective induction of DTH may be accomplished by using BCG vectored vaccines containing selected DNA sequences for T. pallidum antigens.

引用

收藏

页码：576 / 582

页数：7

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