SYNERGISTIC EFFECT OF FLAVONES AND FLAVONOLS AGAINST HERPES-SIMPLEX VIRUS TYPE-1 IN CELL-CULTURE - COMPARISON WITH THE ANTIVIRAL ACTIVITY OF PROPOLIS

被引：244

作者：

AMOROS, M ^{[1
]}

SIMOES, CMO ^{[1
]}

GIRRE, L ^{[1
]}

SAUVAGER, F ^{[1
]}

CORMIER, M ^{[1
]}

机构：

[1] UNIV RENNES 1,FAC PHARM,MICROBIOL PHARMACEUT LAB,F-35010 RENNES,FRANCE

来源：

JOURNAL OF NATURAL PRODUCTS | 1992年 / 55卷 / 12期

关键词：

D O I：

10.1021/np50090a003

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The in vitro activity against herpes simplex virus type 1 of the major flavonoids identified in propolis was investigated. Flavonols were found to be more active than flavones, the order of importance being galangin, kaempferol, and quercetin. The efficacy against HSV-1 of binary flavone-flavonol combinations has been also investigated. The synergy demonstrated by all combinations could explain why propolis is more active than its individual compounds.

引用

页码：1732 / 1740

页数：9

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