PHENOTYPIC CHARACTERIZATION OF LYMPHOCYTE SUB-POPULATIONS IN ESTABLISHED HUMAN PERIODONTAL-DISEASE

被引：166

作者：

SEYMOUR, GJ

GREENSPAN, JS

机构：

[1] UNIV CALIF SAN FRANCISCO,SCH DENT,DEPT ORAL MED & HOSP DENT,SAN FRANCISCO,CA 94143

[2] UNIV LONDON,ROYAL DENT HOSP,SCH DENT SURG,DEPT PATHOL,LONDON,ENGLAND

来源：

JOURNAL OF PERIODONTAL RESEARCH | 1979年 / 14卷 / 01期

关键词：

D O I：

10.1111/j.1600-0765.1979.tb00216.x

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

Phenotypic characterization of lymphoid cell subpopulations in the lesionof established chronic inflammatory periodontal disease in man was carried out using indirect immunofluorescence to dectct the presence of human thymocyte antigen, human myeloid antigen, IgG‐and IgM‐bearing cells in situ in the lesion. The majority of lymphiod cells were IgM‐positive T‐cells were found. These results suggest that established chronic infalmmatory periodontal disease in man should be considered as a B‐cell lesion. The role of the T‐cells in the lesion May be primarily one of helper activity, although cell‐mediated immune mechanisms cannot be precluded. Copyright © 1979, Wiley Blackwell. All rights reserved

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页码：39 / 46

页数：8

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