BIOCHEMICAL AND GENETIC CLASSIFICATION OF RIBOFLAVINE DEFICIENT MUTANTS OF SACCHAROMYCES-CEREVISIAE

被引:60
作者
OLTMANNS, O
BACHER, A
LINGENS, F
ZIMMERMANN, FK
机构
[1] Institut für Mikrobiologie und Molekularbiologie der Universität Hohenheim, Stuttgart-Hohenheim
[2] Forstbotanisches Institut der Universität Freiburg i. Br., Freiburg i. Br.
来源
MOLECULAR AND GENERAL GENETICS | 1969年 / 105卷 / 04期
关键词
D O I
10.1007/BF00277585
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Twenty six riboflavine deficient mutants of Saccharomyces cerevisiae were isolated. They can be divided by biochemical methods into four classes, accumulating (i) no specific product (S), (ii) 2,5-diamino-6-hydroxy-4-ribitylaminopyrimidine (AP), (iii) 5-amino-2,6-dihydroxy-4-ribitylaminopyrimidine (HP), (iv) 6,7-dimethyl-8-ribityllumazine (LU). In genetic experiments six complementation groups were found. Complementation group I is congruent with class S, group II with AP, III and IV with HP and V and VI with LU. In the crosses tested so far, no linkage between complementation groups could be detected by tetrad analysis. Intragenic complementation was found within complementation group V (mutants accumulating LU). © 1969 Springer-Verlag.
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页码:306 / +
页数:1
相关论文
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[11]   ISOLIERUNG VON RIBOFLAVIN-MANGELMUTANTEN VON SACCHAROMYCES CEREVISIAE [J].
OLTMANNS, O ;
LINGENS, F .
ZEITSCHRIFT FUR NATURFORSCHUNG PART B-CHEMIE BIOCHEMIE BIOPHYSIK BIOLOGIE UND VERWANDTEN GEBIETE, 1967, B 22 (07) :751-&