SYNTHESIS OF AN ETHYLENE-GLYCOL CROSS-LINKED AMINO-ACID

被引：10

作者：

HO, MF

WANG, WH

DOUVLOS, M

PHAM, T

KLOCK, T

机构：

[1] Department of Medicinal Chemistry, School of Pharmacy State University of New York at Buffalo, Buffalo

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 10期

关键词：

D O I：

10.1016/S0040-4039(00)79646-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Synthesis of an ethylene glycol-containing amino acid, (2R,9S)-N2-Cbz-N9-Boc-2,9-diamino-4,7-dioxadecanedioic acid 1-phenacyl 10-methyl diester 1, was studied through direct alkylation of N-Boc-L-serine and through BF3-catalyzed ring opening of N-acylaziridinecarboxylates.

引用

页码：1283 / 1286

页数：4

共 12 条

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