PRIMARY STRUCTURE OF A TRISIALYLATED OLIGOSACCHARIDE FROM HUMAN-MILK

被引：16

作者：

FIEVRE, S ^{[1
]}

WIERUSZESKI, JM ^{[1
]}

MICHALSKI, JC ^{[1
]}

LEMOINE, J ^{[1
]}

MONTREUIL, J ^{[1
]}

STRECKER, G ^{[1
]}

机构：

[1] UNIV SCI & TECH LILLE FLANDRES ARTOIS,CHIM BIOL LAB,CNRS,UNITE MIXTE RECH 111,F-59655 VILLENEUVE DASCQ,FRANCE

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1991年 / 177卷 / 02期

关键词：

D O I：

10.1016/0006-291X(91)91847-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A novel oligosaccharide has been isolated from human milk and identified as a trisialylated derivative of lacto-N-hexaose. This compound was purified by combining ion-exchange chromatography, preparative paper chromatography and high performance liquid chromatography. Structural analyses by methylation, fast atom bombardment-mass spectrometry and proton nuclear magnetic resonance spectroscopy are consistent with the following structure: {A figure is presented}. © 1991.

引用

页码：720 / 725

页数：6

共 13 条

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