ENANTIOSELECTIVE ADDITION OF DIETHYLZINC TO ALDEHYDES USING CHIRAL POLYMER CATALYSTS POSSESSING A METHYLENE SPACER

被引：68

作者：

WATANABE, M ^{[1
]}

SOAI, K ^{[1
]}

机构：

[1] SCI UNIV TOKYO,FAC SCI,DEPT APPL CHEM,SHINJUKU KU,TOKYO 162,JAPAN

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1994年 / 07期

关键词：

D O I：

10.1039/p19940000837

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

N-Butylnorephedrine supported on polystyrene resin via a six-methylene spacer catalyses the enantioselective addition of diethylzinc to both aromatic and aliphatic aldehydes, providing optically active secondary alcohols in good to high enantiomeric excesses. In the enantioselective addition of diethylzinc to an aliphatic aldehyde, polymer catalyst with a six-methylene spacer is more enantioselective than other previously reported polymer catalysts.

引用

页码：837 / 842

页数：6

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