ORIGIN OF SERUM ALKALINE PHOSPHATASE IN RAT

被引:56
作者
SAINI, PK
POSEN, S
机构
[1] Departments of Biochemistry and Medicine, University of Sydney, Sydney
基金
英国医学研究理事会;
关键词
D O I
10.1016/0304-4165(69)90062-2
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The increase in alkaline-phosphatase activity which occurs in the serum of the rat after feeding is due, in part, to material inactivated by anti-rat intestinal-alkaline-phosphatase antibody. Feeding also causes the rat's serum alkaline phosphatase to resemble rat intestinal-alkaline-phosphatase in its relative heat resistance, in its electrophoretic migration pattern on starch gel and in its l-phenylalanine sensitivity. Rat intestinal alkaline phosphatase injected intravenously into rats disappers from the circulation of the recipient animals within 2 h. Qualitative differences are described between the alkaline phosphatase obtained from the rat's upper small intestine and that obtained from the lower small intestine. © 1969.
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页码:42 / &
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