INVITRO RESISTANCE OF ARTIFICIAL CONNECTIVE TISSUES TO HUMAN BILE AND PANCREATIC-JUICE

被引：11

作者：

APRAHAMIAN, M ^{[1
]}

DAMGE, C ^{[1
]}

KERRCONTE, J ^{[1
]}

MUTTER, D ^{[1
]}

EVRARD, S ^{[1
]}

MARESCAUX, J ^{[1
]}

机构：

[1] CENT HOSP STRASBOURG,DEPT SURG A,F-67091 STRASBOURG,FRANCE

来源：

BIOMATERIALS | 1992年 / 13卷 / 10期

关键词：

COLLAGEN; ARTIFICIAL MATRIX; BIODEGRADATION;

D O I：

10.1016/0142-9612(92)90130-G

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

The resistance of connective tissue generated from elastin, placenta extracts and human collagen was tested by in vitro incubation with bile and pancreatic juice to investigate the potential use in human digestive surgery. The resistance, determined by macroscopical and microscopical examinations, has been directly compared to those of bovine collagen matrices (Spongel(R), Pangen(R), Helistat(R), Translagen(R)). Only the compact and cross-linked human collagen patch resisted both bile and pancreatic juice. All other biomaterials tested dissolved either in bile or in pancreatic juice. The in vivo behaviour of this new human collagen matrix and its involvement in gastrointestinal wound healing must now be investigated.

引用

页码：697 / 703

页数：7

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