DIAMINES INTERFERE WITH THE TRANSPORT OF L-ORNITHINE IN EHRLICH-CELL PLASMA-MEMBRANE VESICLES

被引:20
作者
MEDINA, MA
URDIALES, JL
DECASTRO, IN
SANCHEZJIMENEZ, F
机构
[1] Lab. de Bioquim. y Biol. Mol., Facultad de Ciencias, Universidad de Malaga
关键词
D O I
10.1042/bj2800825
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
1. L-Ornithine transport by plasma-membrane vesicles isolated from Ehrlich cells is Na+-independent and shows a saturable and a diffusional component. 2. Putrescine, histamine, 5-hydroxytryptamine and 2,3-diaminopropane at 55-mu-M concentration significantly inhibit 0.5 mM-L-ornithine transport, at least for the first 10 min of incubation. 3. There is a trans-stimulatory effect of putrescine on L-orthinine transport.
引用
收藏
页码:825 / 827
页数:3
相关论文
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