GROUP-SPECIFIC CYTOLYTIC ANTIBODY DIRECTED AGAINST THE MAJOR GLYCOPROTEIN (GP70) OF MURINE LEUKEMIA VIRUSES IN SERUM OF MICE WITH DORMANT FLV INFECTIONS

被引：8

作者：

CALLAHAN, RM ^{[1
]}

MARX, PA ^{[1
]}

WHEELOCK, EF ^{[1
]}

机构：

[1] THOMAS JEFFERSON UNIV,DEPT MICROBIOL,PHILADELPHIA,PA 19107

来源：

VIROLOGY | 1979年 / 97卷 / 01期

关键词：

D O I：

10.1016/0042-6822(79)90372-6

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Serum of mice with dormant Friend leukemia virus (FLV) infections contains cytolytic activity against FLC-745 cells, a Friend erythroleukemic cell line. FLC-745 cells express only one cell surface FLV-coded antigen, shown by competition radioimmunoassay experiments to be FLV virion gp70. AKR virus blocks completely the cytolytic activity of serum but cannot block the precipitation of gp70 from detergent-disrupted 125I-labeled cells. These results indicate that the FLC-745 cytolytic antibody in serum from mice with dormant FLV infections is directed against virion gp70 and is group specific. Furthermore, this serum contains a type specific gp70 antibody which is not lytic for FLC-745 cells. © 1979.

引用

页码：55 / 67

页数：13

共 47 条

[1] ROLE OF CARBOHYDRATE IN DETERMINING IMMUNOCHEMICAL PROPERTIES OF MAJOR GLYCOPROTEIN (GP71) OF FRIEND MURINE LEUKEMIA-VIRUS
BOLOGNESI, DP
COLLINS, JJ
LEIS, JP
MOENNIG, V
SCHAFER, W
ATKINSON, PH
[J]. JOURNAL OF VIROLOGY, 1975, 16 (06) : 1453 - 1463
[2] LABELING OF PROTEINS TO HIGH SPECIFIC RADIOACTIVITIES BY CONJUGATION TO A I-125-CONTAINING ACYLATING AGENT - APPLICATION TO RADIOIMMUNOASSAY
BOLTON, AE
HUNTER, WM
[J]. BIOCHEMICAL JOURNAL, 1973, 133 (03) : 529 - 538
[3] BOLTON AE, 1976, 24TH P C BRUGG, P687
[4] CLOYD MW, 1977, CANCER RES, V37, P922
[5] IMMUNOLOGICAL CONTROL OF ASCITES FORM OF MURINE ADENOCARCINOMA 755 .2. TUMOR IMMUNITY ASSOCIATED WITH A FRIEND-MOLONEY-RAUSCHER-TYPE VIRUS
COLLINS, JJ
ROLOSON, G
HAAGENSEN, DE
FISCHINGER, PJ
WELLS, SA
HOLDER, W
BOLOGNESI, DP
[J]. JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1978, 60 (01) : 141 - 152
[6] INTERSPECIES DETERMINANTS OF FRIEND LEUKEMIA-VIRUS ANTIGENS INVOLVED IN CYTOLYSIS OF VIRUS-PRODUCING CELLS
COLLINS, JJ
BOLIO, LD
DENNY, TP
BOLOGNESI, DP
[J]. JOURNAL OF VIROLOGY, 1977, 21 (01) : 113 - 118
[7] IMMUNOTHERAPY OF MURINE LEUKEMIA .1. PROTECTION AGAINST FRIEND LEUKEMIA VIRUS-INDUCED DISEASE BY PASSIVE SERUM THERAPY
COLLINS, JJ
SANFILIPPO, F
TSONGCHOU, L
ISHIZAKI, R
METZGAR, RS
[J]. INTERNATIONAL JOURNAL OF CANCER, 1978, 21 (01) : 51 - 61
[8] SPECIFICITY AND DISTRIBUTION OF DETERMINANTS OF MAJOR GLYCOPROTEIN (GP71) OF MURINE ONCORNAVIRUSES AS DETECTED BY AN INVITRO CYTOTOXICITY ASSAY
COLLINS, JJ
BOLIO, LD
DENNY, TP
BOLOGNESI, DP
[J]. JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1977, 59 (01) : 99 - 106
[9] DAVIES DAL, 1966, IMMUNOLOGY, V11, P115
[10] SYNTHESIS OF AVIAN RNA TUMOR-VIRUS STRUCTURAL PROTEINS
EISENMAN, R
VOGT, VM
DIGGELMANN, H
[J]. COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY, 1974, 39 : 1067 - 1075

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