HUMAN PAPILLOMAVIRUS IN ESOPHAGEAL SQUAMOUS-CELL CARCINOMA

被引：46

作者：

LOKE, SL ^{[1
]}

MA, L ^{[1
]}

WONG, M ^{[1
]}

SRIVASTAVA, G ^{[1
]}

LO, I ^{[1
]}

BIRD, CC ^{[1
]}

机构：

[1] UNIV EDINBURGH, DEPT PATHOL, EDINBURGH EH8 9YL, MIDLOTHIAN, SCOTLAND

来源：

JOURNAL OF CLINICAL PATHOLOGY | 1990年 / 43卷 / 11期

关键词：

D O I：

10.1136/jcp.43.11.909

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

Thirty seven cases of oesophageal squamous cell carcinoma were studied by applying DNA slot blot analysis and in situ hybridisation using type specific probes for HPV 6, 11, 16 and 18. Cases of condyloma accuminata, cervical carcinoma, and laryngeal papilloma were used as controls. Blocks including areas of invasive carcinoma, intraepithelial neoplasia, and normal epithelium were studied in each case. No HPV genome was detectable in any of the oesophageal cases. It is concluded that these types of HPV do not have an association with oesophageal squamous cell carcinoma.

引用

页码：909 / 912

页数：4

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