PROGRESSIVE CYTOMEGALOVIRUS-ENCEPHALITIS DURING SUCCESSFUL THERAPY OF CYTOMEGALOVIRUS-RETINITIS WITH GANCICLOVIR IN AN AIDS-PATIENT

被引：6

作者：

EWIG, S

BIERHOFF, E

LUSTER, W

STEUDEL, A

NIESE, D

机构：

[1] UNIV BONN,INST PATHOL,W-5300 BONN 1,GERMANY

[2] UNIV BONN,RADIOL KLIN,W-5300 BONN 1,GERMANY

来源：

KLINISCHE WOCHENSCHRIFT | 1991年 / 69卷 / 10期

关键词：

AIDS; CYTOMEGALOVIRUS RETINITIS; CYTOMEGALOVIRUS ENCEPHALITIS; GANCICLOVIR; PHARMACOKINETICS;

D O I：

10.1007/BF01666835

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We describe a case of an HIV-infected intravenous drug-abuser who died of progressive cytomegalovirus encephalitis despite successful treatment of cytomegalovirus retinitis with ganciclovir. On autopsy, complete remission of retinitis and widespread cytomegalovirus-encephalitis could be demonstrated. Therapeutic failure therefore seems attributable to insufficient CNS-distribution of ganciclovir rather than to ganciclovir-resistant cytomegalovirus strains.

引用

页码：449 / 453

页数：5

共 21 条

[1] THE DIAGNOSIS OF CYTOMEGALO-VIRUS RETINITIS [J].