STUDY OF BEATING FREQUENCY OF A SINGLE MYOCARDIAL-CELL .3. LASER MICRO-IRRADIATION OF MITOCHONDRIA IN THE PRESENCE OF KCN OR ATP

被引：30

作者：

SALET, C

MORENO, G

VINZENS, F

机构：

[1] Muséum National d' Histoire Naturelle, Laboratoire de Biophysique

来源：

EXPERIMENTAL CELL RESEARCH | 1979年 / 120卷 / 01期

关键词：

D O I：

10.1016/0014-4827(79)90531-7

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Mitochondria of a single rat myocardial cell were irradiated in the visible range with a Q-switched laser microbeam over an area of about 5 μm. The beating frequency was increased in one cell out of three after laser micro-irradiation without appreciable temperature change. The presence of KCN or ATP in the culture medium inhibited this effect. Various mechanisms of stimulation such as membrane damage, mitochondrial Ca2+ release or ATP photoproduction are discussed. The results indicate that change in ATP level is the most likely mechanism of stimulation. © 1979.

引用

页码：25 / 29

页数：5