SYNERGISTIC LETHALITY OF PHAGE T7 BY NEAR-UV RADIATION AND HYDROGEN-PEROXIDE - ACTION SPECTRUM

被引:23
作者
ANANTHASWAMY, HN [1 ]
HARTMAN, PS [1 ]
EISENSTARK, A [1 ]
机构
[1] UNIV MISSOURI,DIV BIOL SCI,COLUMBIA,MO 65201
关键词
D O I
10.1111/j.1751-1097.1979.tb09259.x
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Hydrogen peroxide (H2O2) enhances the killing of phage T7 by near‐ultraviolet irradiation (NUV), maximally at 340 nm. There is no synergistic action below 300 nm. The addition of H2O2 resulted in a marked increase in the number of single strand (SS) DNA breaks induced at all near‐UV wavelengths tested. However, there is no correlation between SS break induction and degree of killing. Copyright © 1979, Wiley Blackwell. All rights reserved
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页码:53 / 56
页数:4
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