DIAGNOSTIC ULTRASOUND - EFFECTS ON THE DNA AND GROWTH-PATTERNS OF ANIMAL-CELLS

被引：81

作者：

LIEBESKIND, D ^{[1
]}

BASES, R ^{[1
]}

ELEQUIN, F ^{[1
]}

NEUBORT, S ^{[1
]}

LEIFER, R ^{[1
]}

GOLDBERG, R ^{[1
]}

KOENIGSBERG, M ^{[1
]}

机构：

[1] YESHIVA UNIV ALBERT EINSTEIN COLL MED,DEPT RADIOL,BRONX,NY 10461

来源：

RADIOLOGY | 1979年 / 131卷 / 01期

关键词：

D O I：

10.1148/131.1.177

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

The effects of diagnostic levels of ultrasound on DNA of Hela cells included: increased immunoreactivity to antinucleoside antibodies in g1 cells, strongly suggestive of unwinding of the helix or singe-strand break induction, and low levels of non-semiconservative synthesis in logarithmically growing cells treated with hydroxyurea, indicating repair synthesis. In the C3H mouse cell line 10T-1/2, Cl 8, loss of contact inhibition with a criss-crossed growth pattern was seen. In one experiment, tumors developed in syngeneic mice at the site of infection of ultrasonically treated cells. Ultrasound in the diagnostic range appears to cause detectable effects on DNA and growth patterns of animal cells.

引用

页码：177 / 184

页数：8

共 38 条

[1]

ABDULLA U, 1971, LANCET, V2, P829

[2] CARCINOGEN-INDUCED IMMUNOREACTIVITY TO ANTINUCLEOSIDE ANTIBODIES IN HELA-CELLS [J].

BASES, R ;

MENDEZ, F ;

NEUBORT, S ;

LIEBESKIND, D ;

HSU, KC .

EXPERIMENTAL CELL RESEARCH, 1976, 103 (01) :175-181

[3] CHROMOSOME BREAKAGE AND ULTRASOUND [J].

BOYD, E ;

ABDULLA, U ;

DONALD, I ;

FLEMING, JEE ;

HALL, AJ ;

FERGUSON.MA .

BRITISH MEDICAL JOURNAL, 1971, 2 (5760) :501-&

[4] INCREASED INCIDENCE OF SISTER CHROMATID EXCHANGES IN RAUSCHER LEUKEMIA-VIRUS INFECTED MOUSE EMBRYO FIBROBLASTS [J].

BROWN, RL ;

CROSSEN, PE .

EXPERIMENTAL CELL RESEARCH, 1976, 103 (02) :418-420

[5] INVESTIGATION INTO POSSIBLE CHROMOSOME DAMAGING EFFECTS OF ULTRASOUND ON HUMAN BLOOD-CELLS [J].

BUCKTON, KE ;

BAKER, NV .

BRITISH JOURNAL OF RADIOLOGY, 1972, 45 (533) :340-&

[6]

CARSON P L, 1978, Ultrasound in Medicine and Biology, V3, P341, DOI 10.1016/0301-5629(78)90076-5

[7] DETECTION OF A NEW ACOUSTOOPTIC EFFECT [J].

CLARK, JA .

PHYSICS LETTERS A, 1975, 54 (01) :81-82

[8] BESSEL FRINGES [J].

CLARK, JA .

OPTICS COMMUNICATIONS, 1976, 16 (01) :141-144

[9]

CLARK JA, 1975, PROGR EXPT MECHANICS, P253

[10] BIOLOGICAL ACTION OF ULTRASOUND IN RELATION TO CELL CYCLE [J].

CLARKE, PR ;

HILL, CR .

EXPERIMENTAL CELL RESEARCH, 1969, 58 (2-3) :443-&

← 1 2 3 4 →