CORRELATIONS AMONG THE DNA BINDING/CLEAVING SPECIFICITIES OF SMALL MOLECULES REVEALED BY DOUBLE-STRAND AFFINITY CLEAVING

被引：6

作者：

GRIFFIN, JH

机构：

[1] Department of Chemistry, Stanford University, Stanford

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1995年 / 5卷 / 01期

关键词：

D O I：

10.1016/0960-894X(94)00461-N

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A DNA double-strand affinity cleaving assay reveals clear positive and negative correlations among the DNA cleavage specificities of a series of minor groove binding/cleaving agents: [SalenMn(III)]+, neocarzinostatin, bleomycin:Fe, and methidiumpropyl-EDTA:Fe.

引用

收藏

页码：73 / 76

页数：4

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