DETECTION OF IGA CLASS ANTIBODY TO HEPATITIS-E VIRUS IN SERUM SAMPLES FROM PATIENTS WITH HEPATITIS-E VIRUS-INFECTION

被引：46

作者：

CHAU, KH

DAWSON, GJ

BILE, KM

MAGNIUS, LO

SJOGREN, MH

MUSHAHWAR, IK

机构：

[1] ABBOTT LABS, EXPTL BIOL RES, N CHICAGO, IL 60064 USA

[2] USA, MED RES INST INFECT DIS, FREDERICK, MD 21701 USA

[3] FAC MED MOGADISHU, DEPT MED, Mogadishu, SOMALIA

[4] NATL BACTERIOL LAB, DEPT VIROL, S-10521 STOCKHOLM, SWEDEN

来源：

JOURNAL OF MEDICAL VIROLOGY | 1993年 / 40卷 / 04期

关键词：

HEPATITIS-E VIRUS HEV; HEV INFECTION; ANTI-HEV ANTIBODIES;

D O I：

10.1002/jmv.1890400414

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

A newly developed assay for IgA class antibody to hepatitis E virus (IgA anti-HEV) was used to study 145 serum samples collected during an outbreak of an enterically transmitted hepatitis that occurred in 3 villages in the lower Shebeli region of Southern Somalia between January, 1988 and November, 1989. A total of 52.4% of the afflicted patients were found positive for IgA anti-HEV, and 73.1% of these were also positive for IgM. Both antibodies disappeared during the convalescence period. Similar results were also seen in serum obtained from sporadic cases of acute waterborne hepatitis in Pakistan. (C) 1993 Wiley-Liss, Inc.

引用

页码：334 / 338

页数：5

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