INCORPORATION OF RADIOACTIVE CALCIUM INTO OTOLITHIC MEMBRANES OF THE GUINEA-PIG AFTER AMINOGLYCOSIDE TREATMENT

被引：22

作者：

MECHIGIAN, I

PRESTON, RE

JOHNSSON, LG

SCHACHT, J

机构：

[1] UNIV MICHIGAN, KRESGE HEARING RES INST, ANN ARBOR, MI 48109 USA

[2] UNIV MICHIGAN, DEPT OTORHINOLARYNGOL, ANN ARBOR, MI 48109 USA

来源：

ACTA OTO-LARYNGOLOGICA | 1979年 / 88卷 / 1-2期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.3109/00016487909137140

中图分类号：

R76 [耳鼻咽喉科学];

学科分类号：

100213 ;

摘要：

The influence of neomycin and streptomycin on the Ca metabolism of the otolithic membranes was investigated in the guinea pig. After chronic treatment with either drug, animals were injected i.p. with radioactive Ca. Retention of Ca in the serum was unaffected by drug treatment, as was the incorporation of radioactivity into bone (femur and otic capsule). Both drugs inhibited the Ca uptake into saccular and utricular otolithic membranes by 30-40%.

引用

页码：56 / 60

页数：5