CRYSTAL-STRUCTURE OF SANDARACOPIMARIC ACID, A LIPOXYGENASE INHIBITOR FROM JUNIPERUS-PHOENICEA

被引：12

作者：

COMTE, G

ALLAIS, DP

SIMON, A

ESSAADY, D

CHULIA, AJ

DELAGE, C

SAUX, M

机构：

[1] FAC PHARM LIMOGES,PHARMACOGNOSIE LAB,EQUIPE BIOMOLEC,F-87025 LIMOGES,FRANCE

[2] FAC PHARM LIMOGES,CHIM PHYS LAB,F-87025 LIMOGES,FRANCE

[3] UNIV BORDEAUX 2,FAC PHARM,SDI,CHIM ANALYT LAB,F-33076 BORDEAUX,FRANCE

来源：

JOURNAL OF NATURAL PRODUCTS-LLOYDIA | 1995年 / 58卷 / 02期

关键词：

D O I：

10.1021/np50116a012

中图分类号：

Q94 [植物学];

学科分类号：

071001 [植物学];

摘要：

The structure of sandaracopimaric acid [1], isolated from a non-polar extract of Juniperus phoenicea, has been determined by X-ray crystallographic analysis. This molecule was also found to be an inhibitor of soybean 15-lipoxygenase with an IC50 value of 0.65 mM.

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页码：239 / 243

页数：5

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