2,4-DIAMINOTHIENO[2,3-D] PYRIMIDINES AS ANTIFOLATES AND ANTIMALARIALS .1. SYNTHESIS OF 2,4-DIAMINO-5,6,7,8-TETRAHYDROTHIANAPHTHENO[2,3-D] PYRIMIDINES AND RELATED COMPOUNDS

被引：60

作者：

ROSOWSKY, A

CHAYKOVSKY, M

CHEN, KKN

LIN, M

MODEST, EJ

机构：

[1] CHILDRENS CANC RES FDN, BOSTON, MA 02115 USA

[2] HARVARD UNIV, MED SCH, DEPT BIOL CHEM, BOSTON, MA 02115 USA

[3] HARVARD UNIV, MED SCH, DEPT PATHOL, BOSTON, MA 02115 USA

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1973年 / 16卷 / 03期

关键词：

D O I：

10.1021/jm00261a002

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：185 / 188

页数：4

共 29 条

[1]

ALBERT A, 1959, HETEROCYCLIC CHEM, P201

[2]

CHACKO AM, 1965, THESIS U N CAROLINA

[3] 2,4-DIAMINOTHIENO [2,3-D] PYRIMIDINES AS ANTIFOLATES AND ANTIMALARIALS .2. SYNTHESIS OF 2,4-DIAMINOPYRIDO [4',3' - 4,5] THIENO [2,3-D] PYRIMIDINES AND 2,4-DIAMINO-8H-THIOPYRANO [4',3' - 4,5] THIENO [2,3-D] PYRIMIDINES [J].

CHAYKOVSKY, M ;

LIN, M ;

ROSOWSKY, A ;

MODEST, EJ .

JOURNAL OF MEDICINAL CHEMISTRY, 1973, 16 (03) :188-191

[4] PYRROLO[2,3-D]PYRIMIDINES [J].

DAVOLL, J .

JOURNAL OF THE CHEMICAL SOCIETY, 1960, (JAN) :131-138

[5] QUINAZOLINE ANALOGUES OF FOLIC ACID [J].

DAVOLL, J ;

JOHNSON, AM .

JOURNAL OF THE CHEMICAL SOCIETY C-ORGANIC, 1970, (08) :997-&

[6] 2,4-DIAMINO-6-ARYLETHYLPTERIDINES AS STREPTOCOCCUS-FAECIUM GROWTH INHIBITORS [J].

DEGRAW, JI ;

BROWN, VH ;

KISLIUK, RL ;

GAUMONT, Y .

JOURNAL OF MEDICINAL CHEMISTRY, 1971, 14 (09) :866-&

[7] FOLATE ANTAGONISTS .6. SYNTHESIS AND ANTIMALARIAL EFFECTS OF FUSED "2,4-DIAMINOTHIENO[2,3-D]PYRIMIDINES [J].

ELSLAGER, EF ;

JACOB, P ;

WERBEL, LM .

JOURNAL OF HETEROCYCLIC CHEMISTRY, 1972, 9 (04) :775-&

[8]

ELSLAGER EF, 1971, 3 INT C HET CHEM SEN, P366

[9] A COMPARATIVE STUDY OF THE USE OF MICROORGANISMS IN THE SCREENING OF POTENTIAL ANTITUMOR AGENTS [J].

FOLEY, GE ;

MCCARTHY, RE ;

BINNS, VM ;

SNELL, EE ;

GUIRARD, BM ;

KIDDER, GW ;

DEWEY, VC ;

THAYER, PS .

ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 1958, 76 (03) :413-441

[10] 2-AMINO-THIOPHENE AUS METHYLENAKTIVEN NITRILEN CARBONYLVERBINDUNGEN UND SCHWEFEL [J].

GEWALD, K ;

SCHINKE, E ;

BOTTCHER, H .

CHEMISCHE BERICHTE-RECUEIL, 1966, 99 (01) :94-&

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