2,4-DIAMINOTHIENO[2,3-D] PYRIMIDINES AS ANTIFOLATES AND ANTIMALARIALS .1. SYNTHESIS OF 2,4-DIAMINO-5,6,7,8-TETRAHYDROTHIANAPHTHENO[2,3-D] PYRIMIDINES AND RELATED COMPOUNDS

被引：60

作者：

ROSOWSKY, A

CHAYKOVSKY, M

CHEN, KKN

LIN, M

MODEST, EJ

机构：

[1] CHILDRENS CANC RES FDN, BOSTON, MA 02115 USA

[2] HARVARD UNIV, MED SCH, DEPT BIOL CHEM, BOSTON, MA 02115 USA

[3] HARVARD UNIV, MED SCH, DEPT PATHOL, BOSTON, MA 02115 USA

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1973年 / 16卷 / 03期

关键词：

D O I：

10.1021/jm00261a002

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：185 / 188

页数：4

共 29 条

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CHEN, KKN ;

MODEST, EJ ;

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[22] QUINAZOLINES .6. SYNTHESIS OF 2,4-DIAMINOQUINAZOLINES FROM ANTHRANILONITRILES [J].

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[23] 2,4-DIAMINOTHIENO [2,3-D] PYRIMIDINES AS ANTIFOLATES AND ANTIMALARIALS .3. SYNTHESIS OF 5,6-DISUBSTITUTED DERIVATIVES AND RELATED TETRACYCLIC ANALOGS [J].

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[24]

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[25] SYNTHESIS OF 2 NEW HETEROCYCLIC RING SYSTEMS - BENZO[3,4]CYCLOHEPTA[1,2-D]-PYRIMIDINES AND BENZO[3,4]CYCLOHEPTA[2,1-D]PYRIMIDINES [J].

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[26] 2,4-DIAMINOPYRIMIDINES . CYCLIZATION OF 6-PHENACYLTHIO AND RELATED DERIVATIVES TO THIENO[2,3-D]PYRIMIDINES AND THIAZOLO[3,2-C]PYRIMIDINES [J].

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[27] THIENO[2,3-D]PYRIMIDINES .1. NEW METHOD FOR PREPARATION OF ESTERS AND AMIDES OF THIENO[2,3-D]PYRIMIDINE-6-CARBOXYLIC ACIDS [J].

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[28] A liquid bath melting point apparatus [J].

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