STUDIES ON THE CLASTOGENIC EFFECTS OF BIOLOGIC STAINS AND DYES

被引:62
作者
AU, W
HSU, TC
机构
[1] Department of Biology, University of Texas System Cancer Center, M. D. Anderson Hospital and Tumor Institute, Houston
来源
ENVIRONMENTAL MUTAGENESIS | 1979年 / 1卷 / 01期
关键词
chromosome breakage; dyes; stains;
D O I
10.1002/em.2860010109
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
We have surveyed the clastogenic potential of 12 different groups of stains and dyes totalling 48 compounds. We observed that 18 compounds induced significant increase in chromosome damage. Most of them were also found to be mutagenic, carcinogenic, or toxic in other reported studies. However, no significant studies were reported on six of them. It is concluded that these agents are potentially hazardous and should be studied further in detail. Copyright © 1979 Wiley‐Liss, Inc., A Wiley Company
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页码:27 / 35
页数:9
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