THE REMARKABLE EFFECT OF ZNCL2 AN ASYMMETRIC ENOLIZATION REACTIONS OF CHIRAL BASES

被引：19

作者：

COGGINS, P ^{[1
]}

GAUR, S ^{[1
]}

SIMPKINS, NS ^{[1
]}

机构：

[1] UNIV NOTTINGHAM,DEPT CHEM,NOTTINGHAM NG7 2RD,ENGLAND

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 09期

关键词：

D O I：

10.1016/0040-4039(95)00044-D

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The addition of ZnCl2 to the chiral lithium amide base 3 dramatically affects the level of asymmetric induction observed in asymmetric enolisation reactions of certain cyclic ketones, the enantiometic excess of aldol produce obtained increasing on addition of ca. 0.4 equivalents of ZnCl2 but men decreasing again if more ZnCl2 is employed.

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页码：1545 / 1548

页数：4

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