SYNTHESIS OF PYRANOTROPANES VIA ENANTIOSELECTIVE DEPROTONATION STRATEGY

被引：35

作者：

MAJEWSKI, M

LAZNY, R

机构：

[1] Department of Chemistry, University of Saskatchewan, Saskatoon

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 22期

关键词：

D O I：

10.1016/S0040-4039(00)73063-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Synthesis of tropane alkaloids darlingine, chalcostrobamine and isobellendine both in the racemic form and as unnatural enantiomers is described. Enantioselective deprotonation of tropinone, which proceeded with ca 90% ee, was the key step in each of the syntheses. Enantioselectivity was increased in the presence of LiCl.

引用

页码：3653 / 3656

页数：4

共 18 条

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