PCR DETECTION OF DISTAL YP-SEQUENCES IN AN XX TRUE HERMAPHRODITE

被引：75

作者：

NAKAGOME, Y

SEKI, S

FUKUTANI, K

NAGAFUCHI, S

NAKAHORI, Y

TAMURA, T

机构：

[1] UNIV TOKYO,BRANCH HOSP,DEPT UROL,TOKYO 113,JAPAN

[2] KYORIN UNIV,SCH HLTH SCI,DEPT CLIN GENET,MITAKA,TOKYO 181,JAPAN

来源：

AMERICAN JOURNAL OF MEDICAL GENETICS | 1991年 / 41卷 / 01期

关键词：

HERMAPHRODITISM; TRUE HERMAPHRODITISM; X-Y CROSSING OVER; SRY; ZFY; PABY;

D O I：

10.1002/ajmg.1320410127

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

An XX true hermaphrodite was examined for the presence of Y-specific sequences using Southern-blotting and polymerase chain reaction (PCR) techniques. Of 25 loci examined, only two, the proximal border of the pseudoautosomal region (PABY) and the sex determining region of the Y chromosome (SRY), were detected. A crossing over event in paternal meiosis, proximal to the SRY locus but distal to the zinc finger protein (ZFY) locus, presumably transferred to two loci to the X chromosome.

引用

页码：112 / 114

页数：3

共 13 条

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