DESIGN AND SYNTHESIS OF A PROTOTYPE MODEL ANTAGONIST OF TACHYKININ NK-2 RECEPTOR

被引：35

作者：

HANESSIAN, S ^{[1
]}

RONAN, B ^{[1
]}

LAOUI, A ^{[1
]}

机构：

[1] RHONE POULENC RORER SA, CENT RES, CTR RECH VITRY ALFORTVILLE, F-94403 VITRY, FRANCE

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1994年 / 4卷 / 11期

关键词：

D O I：

10.1016/S0960-894X(01)80369-3

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A conformationally biased bicyclic lactam containing strategically placed hydrophobic groups was synthesized as a prototype model antagonist molecule of the NK-2 receptor.

引用

页码：1397 / 1400

页数：4

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