MOLECULAR CHARACTERIZATION AND FUNCTIONAL-ANALYSIS OF THE MAJOR AUTOLYSIN OF STAPHYLOCOCCUS-AUREUS-8325/4

被引：122

作者：

FOSTER, SJ

机构：

[1] Molecular Biol./Biotechnology Dept., University of Sheffield, Western Bank, Sheffield S10 2TN, Firth Court

来源：

JOURNAL OF BACTERIOLOGY | 1995年 / 177卷 / 19期

关键词：

D O I：

10.1128/jb.177.19.5723-5725.1995

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The gene encoding the major autolysin of Staphylococcus aureus 8325/4 has been cloned, sequenced, and insertionally inactivated. The three-domain, 137,384-Da protein has a C-terminal glucosaminidase active site and is involved in cell separation, generalized cell lysis, and release of wall material at the cell surface. Expression occurs throughout growth and is stimulated by low temperatures and in the presence of 1 M NaCl.

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页码：5723 / 5725

页数：3

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