A FACILE SYNTHESIS OF STEROIDAL DELTA(4)-3-KETONES USING PYRIDINIUM CHLOROCHROMATE (PCC)

被引：10

作者：

PARISH, EJ

HONDA, H

机构：

[1] Department of Chemistry, Auburn University, AL

来源：

SYNTHETIC COMMUNICATIONS | 1990年 / 20卷 / 08期

关键词：

D O I：

10.1080/00397919008052824

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Pyridinium chlorochromate(PCC), in refluxing benzene, has been found to be an effective and convenient reagent for the oxidation and concomitant isomerization of steroidal Δ5-3β-alcohols to the corresponding Δ-3-ketones in high yield. Copyright © 1990 by Taylor & Francis Group. All rights reserved.

引用

收藏

页码：1167 / 1174

页数：8

相关论文

共 26 条

[21] PYRIDINIUM CHLOROCHROMATE-MEDIATED ALLYLIC AND BENZYLIC OXIDATION [J].

PARISH, EJ ;

CHITRAKORN, S ;

WEI, TY .

SYNTHETIC COMMUNICATIONS, 1986, 16 (11) :1371-1375

[22] CHEMICAL SYNTHESIS OF 4,4'-DIMETHYL-7-OXYGENATED STEROLS - INHIBITORS OF 3-HYDROXY-3-METHYLGLUTARYL REDUCTASE [J].

PARISH, EJ ;

CHITRAKORN, S ;

TAYLOR, FR ;

SAUCIER, SE .

CHEMISTRY AND PHYSICS OF LIPIDS, 1984, 36 (02) :179-188

[23] PYRIDINIUM CHLOROCHROMATE - A VERSATILE OXIDANT IN ORGANIC-SYNTHESIS [J].

PIANCATELLI, G ;

SCETTRI, A ;

DAURIA, M .

SYNTHESIS-STUTTGART, 1982, 1982 (04) :245-258

[24] INHIBITORS OF STEROL SYNTHESIS - CHEMICAL SYNTHESES, PROPERTIES AND EFFECTS OF 4,4-DIMETHYL-15-OXYGENATED STEROLS ON STEROL SYNTHESIS AND ON 3-HYDROXY-3-METHYLGLUTARYL COENZYME-A REDUCTASE-ACTIVITY IN CULTURED MAMMALIAN-CELLS [J].

SCHROEPFER, GJ ;

PARISH, EJ ;

TSUDA, M ;

KANDUTSCH, AA .

CHEMISTRY AND PHYSICS OF LIPIDS, 1988, 47 (03) :187-207

[25] THE SYNTHESIS OF LANOSTEROL (LANOSTADIENOL) [J].

WOODWARD, RB ;

PATCHETT, AA ;

BARTON, DHR ;

IVES, DAJ ;

KELLY, RB .

JOURNAL OF THE CHEMICAL SOCIETY, 1957, (MAR) :1131-1144

[26] THE SYNTHESIS OF LANOSTENOL [J].

WOODWARD, RB ;

PATCHETT, AA ;

BARTON, DHR ;

IVES, DAJ ;

KELLY, RB .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1954, 76 (10) :2852-2853