A STRUCTURAL BASIS FOR TRANSPHOSPHORYLATION OF NUCLEOTIDES WITH HYDROXYAPATITE

被引：22

作者：

TAVES, DR

REEDY, RC

机构：

[1] Department of Radiation Biology and Biophysics, University of Rochester School of Medicine and Dentistry, Rochester, 14620, New York

来源：

CALCIFIED TISSUE RESEARCH | 1969年 / 3卷 / 03期

关键词：

Adenosine triphosphate; Hydroxyapatite; Nucleotides; Pyrophosphate; Transphosphorylation;

D O I：

10.1007/BF02058670

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

The basis for transphosphorylation between nucleotides and hydroxyapatite (HA) has been explored. Using a recently-proposed model for the surface of HA and the structure of 2- and 3-membered polyphosphates, a reasonable atomic explanation can be shown for this reaction. Transphosphorylation has been found to result in a pyrophosphate on HA which is distinctive from pyrophosphate absorbed onto HA from solution. The models suggest that this distinction is due to a different orientation of the pyrophosphate on the surface of the HA depending on the origin of the pyrophosphate. © 1969 Springer-Verlag.

引用

页码：284 / &