DETERMINANTS OF TRANSLATIONAL FIDELITY AND EFFICIENCY IN VERTEBRATE MESSENGER-RNAS

被引:120
作者
KOZAK, M
机构
[1] Department of Biochemistry, University of Medicine and Dentistry of New Jersey, Piscataway, NJ 08854
关键词
INITIATION OF TRANSLATION; SCANNING MODEL; MESSENGER-RNA STRUCTURE;
D O I
10.1016/0300-9084(94)90182-1
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
This article reviews current knowledge on the mechanisms affecting the fidelity of initiation codon selection, and discusses the effects of structural features in the 5'-non-coding region on the efficiency of translation of messenger RNA molecules.
引用
收藏
页码:815 / 821
页数:7
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